What is the most likely diagnosis for a patient with the following CBC findings? WBC: 8.8 × 103/µl; RBC: 3.01 × 103/µl; Hgb: 10.3 g/dL; Hct: 32.2%; MCV: 74 fL; MCHC: 28.3 g/dL; Plt: 400 × 103/µl; RDW: 18.4%; Reticulocytes: 2.1%.
Identify which anemia is the patient experiencing, which tests should be ordered and what type of treatment should be followed.
Full Answer Section
While iron deficiency is the most likely diagnosis, other possibilities like thalassemia (also a microcytic anemia) should be considered.
To confirm the diagnosis and determine the underlying cause, the following tests should be ordered:
- Serum iron levels: Measures the amount of iron in the blood.
- Ferritin levels: Reflects the body's iron stores.
- Total iron-binding capacity (TIBC): Measures the blood's capacity to bind iron.
- Transferrin saturation: The percentage of transferrin that is bound to iron.
- Blood smear examination: A microscopic examination of the blood cells to look for abnormalities in their size, shape, and color.
The treatment will depend on the underlying cause of the anemia:
- If iron-deficiency anemia is confirmed: Iron supplementation, either orally or intravenously, is the primary treatment. The underlying cause of the iron deficiency, such as poor dietary intake, blood loss, or malabsorption, should also be addressed.
- If the anemia is severe: Blood transfusions may be necessary to quickly increase the number of red blood cells and improve oxygen delivery to the tissues.