Hirsutism versus hypertrichosis

Let's start by discussing hirsutism versus hypertrichosis. What’s the difference?
How would one classify or score hirsutism?
SCENARIO 2
A 28-year-old, premenopausal woman of Middle Eastern ethnicity comes to the outpatient department with complaints of unwanted hair growth on her upper lip, chin, and chest. She describes generally regular menstruation of between 28-35 days. She has normal hair growth in the axilla and pubic region. The scalp hair is normal. She has unusually thick hair growth on her eyebrows which is also concerning for her. The clinician calculates her modified Ferriman–Gallwey score as 12.
Which investigations would you request for this woman?

  Thesis Statement: Hirsutism and hypertrichosis are two distinct conditions characterized by excessive hair growth, with hirsutism being associated with hormonal imbalances, and a modified Ferriman-Gallwey score of 12 in a 28-year-old Middle Eastern woman suggests the need for specific investigations to determine the underlying cause. Understanding the Difference: Hirsutism is a condition characterized by excessive hair growth in areas typically associated with male patterns, such as the face, chest, and back, in women. It is often caused by an underlying hormonal imbalance, particularly an increase in androgen levels. On the other hand, hypertrichosis refers to excessive hair growth that can occur in any area of the body and can be generalized or localized, often due to genetic or acquired factors such as medications or underlying medical conditions. Classifying and Scoring Hirsutism: The modified Ferriman-Gallwey score is a common method for assessing the degree of hirsutism. This scoring system evaluates hair growth in nine different body areas, with a maximum score of 36. A score of 8 or higher is considered indicative of hirsutism. Investigations for the Woman: Given the symptoms described by the 28-year-old woman, specific investigations would be warranted to determine the underlying cause of her hirsutism. These may include: Blood tests to assess hormone levels, including testosterone, dehydroepiandrosterone sulfate (DHEAS), luteinizing hormone (LH), follicle-stimulating hormone (FSH), and prolactin. Thyroid function tests to evaluate for thyroid disorders that could contribute to hirsutism. Imaging studies such as ultrasound to assess the ovaries for polycystic ovary syndrome (PCOS) or other structural abnormalities. Evaluation for other potential underlying conditions such as adrenal gland disorders. In conclusion, hirsutism and hypertrichosis are distinct conditions characterized by excessive hair growth, with hirsutism often linked to hormonal imbalances. The modified Ferriman-Gallwey score is a valuable tool for evaluating the degree of hirsutism. For the 28-year-old Middle Eastern woman presenting with hirsutism and a score of 12, specific investigations such as hormone tests, thyroid function tests, imaging studies, and evaluation for underlying conditions would be crucial in determining the underlying cause of her symptoms.        

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